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RON5 Is Critical for Organization and Function of the Toxoplasma Moving Junction Complex

20 Mar 2014

Abstract excerpt

Apicomplexans facilitate host cell invasion through formation of a tight-junction interface between parasite and host plasma membranes called the moving junction (MJ). A complex of the rhoptry neck proteins RONs 2/4/5/8 localize to the MJ during invasion where they are believed to provide a stable anchoring point for host penetration. During the initiation of invasion, the preformed MJ RON complex is injected...

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PMID: 24651769
DOI: 10.1371/journal.ppat.1004025

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