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Article

Association of genetic variants of the α-kinase 1 gene with myocardial infarction in community-dwelling individuals

30 Oct 2013

Abstract excerpt

We previously demonstrated that rs2074380 (G→A, Gly870Ser) and rs2074381 (A→G, Asn916Asp) of the α‑kinase 1 gene (ALPK1) were significantly associated with chronic kidney disease (CKD) in individuals with diabetes mellitus. As CKD is a significant risk factor for coronary heart disease, we hypothesized that rs2074380 and rs2074381 of ALPK1 may contribute to the genetic susceptibility to myocardial infarction (MI)...

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PMID: 24649083
DOI: 10.3892/br.2013.190

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