Article
Mutation profiling of the hepatitis B virus strains circulating in North Indian population.
PloS one - 1 Jan 2014
Tuteja Amit, Siddiqui Abu Baker, Madan Kaushal, Goyal Rohit, Shalimar, Sreenivas Vishnubhatla, Kaur Navkiran, Panda Subrat K, Narayanasamy Krishnamoorthy, Subodh Swati, Acharya Subrat K
Abstract excerpt
AIMS: The aim of this study was to investigate the genomic mutations in the circulating Hepatitis B virus strains causing infection in the Indian population. Further, we wanted to analyze the biological significance of these mutations in HBV mediated disease. METHODS: 222 HBsAg positive patients were enrolled in the study. The genotype and mutation profile was determined for the infecting HBV isolate by...
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