Article
Comparison of human saliva and synthetic histo-blood group antigens usage as ligands in norovirus-like particle binding and blocking assays.
Microbes and infection - 1 Jun 2014
Uusi-Kerttula Hanni, Tamminen Kirsi, Malm Maria, Vesikari Timo, Blazevic Vesna
Abstract excerpt
Blocking of norovirus-like particle binding to their cellular ligands, histo-blood group antigens with immune sera, is considered a surrogate norovirus neutralization assay. We compared human secretor positive saliva and synthetic biotinylated carbohydrates as a source of histo-blood group antigens in binding and blocking assays. Six norovirus capsid-derived virus-like particles belonging to genogroup I...
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