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Article

Investigation of the Rho-kinase Gene Polymorphism in Primary Open-angle Glaucoma.

Ophthalmic genetics - 1 Jan 2016

Demiryürek Seniz, Okumus Seydi, Bozgeyik İbrahim, Oztuzcu Serdar, Coskun Erol, Mat Emrah, Durucu Ela, Tatar Mehmet G, Erbagci İbrahim, Gürler Bülent, Demiryürek Abdullah T

Abstract excerpt

PURPOSE: Genetic factors are shown to have a role in the development of primary open-angle glaucoma (POAG). The aim of this study was to determine the effects of genetic polymorphisms of Rho-kinase (ROCK) genes on the risk of POAG in a Turkish population. METHODS: Genomic DNA was extracted from leukocytes of the peripheral blood, and 8 single nucleotide polymorphisms in the ROCK1 and ROCK2 genes were analysed in...

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Source

Identifiers

PMID: 24617500
DOI: 10.3109/13816810.2014.895016

Genes

ROCK1
ROCK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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