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JAK2-Centered Interactome Hotspot Identified by an Integrative Network Algorithm in Acute Stanford Type A Aortic Dissection

24 Feb 2014

Abstract excerpt

The precise mechanisms underlying dissections, especially those without connective tissue diseases or congenital vascular diseases, are incompletely understood. This study attempted to identify both the expression profile of the dissected ascending aorta and the interactome hotspots associated with the disease, using microarray technology and gene regulatory network analysis. There were 2,737 genes differentially...

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Aortic aneurysm repair treatments
Aortic Disease and Treatment Approaches
Galectins and Cancer Biology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24586754
DOI: 10.1371/journal.pone.0089406

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