Article
A homolog of splicing factor SF1 is essential for development and is involved in the alternative splicing of pre-mRNA in Arabidopsis thaliana.
The Plant journal : for cell and molecular biology - 1 May 2014
Jang Yun Hee, Park Hyo-Young, Lee Keh Chien, Thu May Phyo, Kim Soon-Kap, Suh Mi Chung, Kang Hunseung, Kim Jeong-Kook
Abstract excerpt
During initial spliceosome assembly, SF1 binds to intron branch points and interacts with U2 snRNP auxiliary factor 65 (U2AF65). Here, we present evidence indicating that AtSF1, the Arabidopsis SF1 homolog, interacts with AtU2AF65a and AtU2AF65b, the Arabidopsis U2AF65 homologs. A mutant allele of AtSF1 (At5g51300) that contains a T-DNA insertion conferred pleiotropic developmental defects, including early...
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