Article
Coronary artery ectasia is associated with the c.894G>T (Glu298Asp) polymorphism of the endothelial nitric oxide synthase gene.
The Tohoku journal of experimental medicine - 1 Feb 2014
Arif Yalcin Ahmet, Faruk Akturk Ibrahim, Celik Omer, Erturk Mehmet, Sabri Hancer Veysel, Yalcin Burce, Isiksacan Nilgun, Uzun Fatih, Ozbey Ozyilmaz Sinem, Biyik Ismail
Abstract excerpt
Coronary artery ectasia (CAE) is characterized by inappropriate dilation of the coronary vasculature. The underlying mechanisms of CAE formation are not yet entirely known. A polymorphism in the endothelial nitric oxide synthase (eNOS) gene, which reduces eNOS activity, might be a risk factor for coronary heart diseases. However, its role in CAE is unknown. One of the most studied eNOS gene polymorphisms is a...
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