Article
Cellular phenotype and extracellular vesicles: basic and clinical considerations.
Stem cells and development - 1 Jul 2014
Quesenberry Peter J, Goldberg Laura R, Aliotta Jason M, Dooner Mark S, Pereira Mandy G, Wen Sicheng, Camussi Giovanni
Abstract excerpt
Early work on platelet and erythrocyte vesicles interpreted the phenomena as a discard of material from cells. Subsequently, vesicles were studied as possible vaccines and, most recently, there has been a focus on the effects of vesicles on cell fate. Recent studies have indicated that extracellular vesicles, previously referred to as microvesicles or exosomes, have the capacity to change the phenotype of...
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