Article
Extracellular Vesicles as Signaling Mediators and Disease Biomarkers across Biological Barriers.
International journal of molecular sciences - 4 Apr 2020
Simeone Pasquale, Bologna Giuseppina, Lanuti Paola, Pierdomenico Laura, Guagnano Maria Teresa, Pieragostino Damiana, Del Boccio Piero, Vergara Daniele, Marchisio Marco, Miscia Sebastiano, Mariani-Costantini Renato
Abstract excerpt
Extracellular vesicles act as shuttle vectors or signal transducers that can deliver specific biological information and have progressively emerged as key regulators of organized communities of cells within multicellular organisms in health and disease. Here, we survey the evolutionary origin, general characteristics, and biological significance of extracellular vesicles as mediators of intercellular signaling,...
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