Article
Homeostatic actin cytoskeleton networks are regulated by assembly factor competition for monomers.
Current biology : CB - 3 Mar 2014
Burke Thomas A, Christensen Jenna R, Barone Elisabeth, Suarez Cristian, Sirotkin Vladimir, Kovar David R
Abstract excerpt
Controlling the quantity and size of organelles through competition for a limited supply of components is quickly emerging as an important cellular regulatory mechanism. Cells assemble diverse actin filament (F-actin) networks for fundamental processes including division, motility, and polarization. F-actin polymerization is tightly regulated by activation of assembly factors such as the Arp2/3 complex and...
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