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Article

Satiety mechanisms in genetic risk of obesity.

JAMA pediatrics - 1 Apr 2014

Llewellyn Clare Heidi, Trzaskowski Maciej, van Jaarsveld Cornelia Hendrika Maria, Plomin Robert, Wardle Jane

Abstract excerpt

IMPORTANCE: A better understanding of the cause of obesity is a clinical priority. Obesity is highly heritable, and specific genes are being identified. Discovering the mechanisms through which obesity-related genes influence weight would help pinpoint novel targets for intervention. One potential mechanism is satiety responsiveness. Lack of satiety characterizes many monogenic obesity disorders, and lower...

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Identifiers

PMID: 24535189
DOI: 10.1001/jamapediatrics.2013.4944
PMCID: PMC3981891

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