Article
The good and the bad of being connected: the integrons of aging.
Current opinion in cell biology - 1 Feb 2014
Dillin Andrew, Gottschling Daniel E, Nyström Thomas
Abstract excerpt
Over 40 years ago, Francois Jacob proposed that levels of 'integrons' explain how biological systems are constructed. Today, these networks of interactions between tissues, cells, organelles, metabolic pathways, genes, and individual molecules provide key insights into biology. We suggest that the wiring and interdependency between subsystems within a network are useful to understand the aging process. The...
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