Article
De novo reconstruction of consensus master genomes of plant RNA and DNA viruses from siRNAs.
PloS one - 1 Jan 2014
Seguin Jonathan, Rajeswaran Rajendran, Malpica-López Nachelli, Martin Robert R, Kasschau Kristin, Dolja Valerian V, Otten Patricia, Farinelli Laurent, Pooggin Mikhail M
Abstract excerpt
Virus-infected plants accumulate abundant, 21-24 nucleotide viral siRNAs which are generated by the evolutionary conserved RNA interference (RNAi) machinery that regulates gene expression and defends against invasive nucleic acids. Here we show that, similar to RNA viruses, the entire genome sequ...
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