Article
Genetic variation is the major determinant of individual differences in leukocyte endothelial adhesion.
PloS one - 1 Jan 2014
Grassi Michael A, Rao Vidhya, Winkler Kathryn P, Zhang Wei, Bogaard Joseph D, Chen Siquan, LaCroix Bonnie, Lenkala Divya, Rehman Jalees, Malik Asrar B, Cox Nancy J, Huang R Stephanie
Abstract excerpt
OBJECTIVE: To determine the genetic contribution to leukocyte endothelial adhesion. METHODS: Leukocyte endothelial adhesion was assessed through a novel cell-based assay using human lymphoblastoid cell lines. A high-throughput screening method was developed to evaluate the inter-individual variability in leukocyte endothelial adhesion using lymphoblastoid cell lines derived from different donors. To assess...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.