Article
CYP1A1 and CYP2E1 genotypes and risk of esophageal squamous cell carcinoma in a high-incidence region, Kashmir.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jun 2014
Bhat Gulzar Ahmad, Shah Idrees Ayoub, Makhdoomi Muzamil Ashraf, Iqbal Beenish, Rafiq Rumaisa, Nabi Sumaiya, Masood Akbar, Lone Mohd Maqbool, Dar Nazir Ahmad
Abstract excerpt
The study analyzed the relationship between genetic polymorphisms of phase I xenobiotic metabolizing enzymes, cytochromes P450 (CYP) 1A1 and CYP2E1 and esophageal squamous cell carcinoma (ESCC) in Kashmir, India. The different genotypes of CYP1A1 and CYP2E1 were analyzed by polymerase chain reaction and restriction fragment length polymorphism in 526 ESCC cases and equal number of matched controls. Conditional...
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