Article
Imputation of non-genotyped individuals based on genotyped relatives: assessing the imputation accuracy of a real case scenario in dairy cattle.
Genetics, selection, evolution : GSE - 3 Feb 2014
Bouwman Aniek C, Hickey John M, Calus Mario P L, Veerkamp Roel F
Abstract excerpt
BACKGROUND: Imputation of genotypes for ungenotyped individuals could enable the use of valuable phenotypes created before the genomic era in analyses that require genotypes. The objective of this study was to investigate the accuracy of imputation of non-genotyped individuals using genotype information from relatives. METHODS: Genotypes were simulated for all individuals in the pedigree of a real (historical)...
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