Article
Incontinentia pigmenti: learning disabilities are a fundamental hallmark of the disease.
PloS one - 1 Jan 2014
Pizzamiglio Maria Rosa, Piccardi Laura, Bianchini Filippo, Canzano Loredana, Palermo Liana, Fusco Francesca, D'Antuono Giovanni, Gelmini Chiara, Garavelli Livia, Ursini Matilde Valeria
Abstract excerpt
Studies suggest that genetic factors are associated with the etiology of learning disabilities. Incontinentia Pigmenti (IP, OMIM#308300), which is caused by mutations of the IKBKG/NEMO gene, is a rare X-linked genomic disorder (1:10000/20:000) that affects the neuroectodermal tissues. It always affects the skin and sometimes the hair, teeth, nails, eyes and central nervous system (CNS). Data from IP patients...
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