Article
Non-thermal atmospheric pressure plasma induces apoptosis in oral cavity squamous cell carcinoma: Involvement of DNA-damage-triggering sub-G(1) arrest via the ATM/p53 pathway.
Archives of biochemistry and biophysics - 1 Mar 2014
Chang Jae Won, Kang Sung Un, Shin Yoo Seob, Kim Kang Il, Seo Seong Jin, Yang Sang Sik, Lee Jong-Soo, Moon Eunpyo, Baek Seung Jae, Lee Keunho, Kim Chul-Ho
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Abstract excerpt
Recent advances in physics have made possible the use of non-thermal atmospheric pressure plasma (NTP) in cancer research. Although increasing evidence suggests that NTP induces death of various cancer cell types, thus offering a promising alternative treatment, the mechanism of its therapeutic effect is little understood. In this study, we report for the first time that NTP led to apoptotic cell death in oral...
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