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Article

Characterization of interstitial Cajal progenitors cells and their changes in Hirschsprung's disease.

PloS one - 1 Jan 2014

Chen Zhi-Hua, Zhang Yong-Chang, Jiang Wei-Fang, Yang Cissy, Zou Gang-Ming, Kong Yu, Cai Wei

Abstract excerpt

Interstitial cells of Cajal (ICC) are critical to gastrointestinal motility. The phenotypes of ICC progenitors have been observed in the mouse gut, but whether they exist in the human colon and what abnormal changes in their quantity and ultrastructure are present in Hirschsprung's disease (HSCR) colon remains uncertain. In this study, we collected the surgical resection of colons, both proximal and narrow...

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Identifiers

PMID: 24475076
DOI: 10.1371/journal.pone.0086100
PMCID: PMC3901676

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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