Article
[Genetic analyses as basis for a personalized medicine in patients with coronary artery disease].
Herz - 1 Mar 2014
Kessler T, Kaess B, Bourier F, Erdmann J, Schunkert H
Abstract excerpt
Knowledge about the etiology of coronary artery disease (CAD) entered new dimensions using genome-wide association studies. The current situation is that 46 chromosomal loci have been identified to be associated with CAD with genome-wide significance, i.e. p<5×10(-8), in Western Europeans. As the individual DNA sequence remains unchanged after fertilization, the risk variants cannot occur due to confounders, such...
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