Article
Monochorionic twins discordant for mosaic trisomy 14.
American journal of medical genetics. Part A - 1 May 2014
He Mai, Pepperell John R, Gundogan Fusun, De Paepe Monique E, Maggio Lindsay, Lu Shaolei, Kostadinov Stefan, O'Brien Barbara, Delamonte Suzanne, Pinar Halit, Tantravahi Umadevi
Abstract excerpt
Monochorionic-diamniotic twins are usually monozygotic twins and known to be associated with adverse obstetric and perinatal outcomes. Cases of discordant karyotype of monozygotic twins are rare and most involves sex chromosomes. We present the first case of monochorionic twins with discordant ka...
Topics
- Alleles
- Autopsy
- Chromosomes, Human, Pair 14
- Comparative Genomic Hybridization
- Fatal Outcome
- Female
- Genotype
- Humans
- Karyotyping
- Magnetic Resonance Imaging
- Mosaicism
- Polymorphism, Single Nucleotide
- Trisomy
- Twins, Monozygotic
- Ultrasonography, Prenatal