Article
Monozygotic twins discordant for 18q21.2qter deletion detected by array CGH in amniotic fluid.
European journal of medical genetics - 1 Sept 2013
Essaoui M, Nizon M, Beaujard M P, Carrier A, Tantau J, de Blois M C, Fontaine S, Michot C, Amiel J, Bernard J P, Attié-Bitach T, Vekemans M, Turleau C, Ville Y, Malan V
Abstract excerpt
Discordant chromosomal anomalies in monozygotic twins may be caused by various timing issues of erroneous mitosis and twinning events. Here, we report a prenatal diagnosis of heterokaryotypic monozygotic twins discordant for phenotype. In a 28-year-old woman, ultrasound examination performed at 2...
Topics
- Adult
- Amniotic Fluid
- Chromosome Deletion
- Chromosome Disorders
- Chromosomes, Human, Pair 18
- Cleft Palate
- Comparative Genomic Hybridization
- Diseases in Twins
- Female
- Fetal Growth Retardation
- Humans
- Microsatellite Repeats
- Mosaicism
- Phenotype