Molecular Diagnosis of Periprosthetic Joint Infection by Quantitative RT‐PCR of Bacterial 16S Ribosomal RNA

Abstract excerpt

The diagnosis of periprosthetic joint infection is sometimes straightforward with purulent discharge from the fistula tract communicating to the joint prosthesis. However it is often difficult to differentiate septic from aseptic loosening of prosthesis because of the high culture-negative rates in conventional microbiologic culture. This study used quantitative reverse transcription polymerase chain reaction...

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