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Article

The 5-HT₁A receptor C(1019)G polymorphism influences the intravaginal ejaculation latency time in Dutch Caucasian men with lifelong premature ejaculation.

Pharmacology, biochemistry, and behavior - 1 Jun 2014

Janssen Paddy K C, van Schaik R, Zwinderman Aeilko H, Olivier Berend, Waldinger Marcel D

Abstract excerpt

INTRODUCTION: Lifelong premature ejaculation (LPE) is characterized by persistent intravaginal ejaculation latency times (IELTs) of less than 1 min, and has been postulated as a neurobiological dysfunction related to diminished serotonergic neurotransmission with 5-HT₁A receptor hyperfunction and 5-HT₂C hypofunction. AIM: To investigate the relationship between 5-HT₁A receptor gene (HTR₁A)-C(1019)G promoter...

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Identifiers

PMID: 24440118
DOI: 10.1016/j.pbb.2014.01.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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