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Article

A meta-analysis of the effects of the 5-hydroxytryptamine transporter gene-linked promoter region polymorphism on susceptibility to lifelong premature ejaculation.

PloS one - 1 Jan 2013

Zhu Lijie, Mi Yuanyuan, You Xiaoming, Wu Sheng, Shao Hongbao, Dai Feng, Peng Tao, Qin Feng, Feng Ninghan

Abstract excerpt

OBJECTIVE: Premature ejaculation (PE) has been reported as the most common male sexual dysfunction with global prevalence rates estimated at approximately 30%. The neurobiogenesis of ejaculation is very complex and involves the serotoninergic (5-hydroxytryptamine, 5-HT) system. Recently, genetic polymorphisms located on SLC6A4 gene codifying for 5-HT transporter (5-HTT), the major regulator of serotonic...

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Share to HTT gene
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Promoter Regions, Genetic

Share to Serotonin Plasma Membrane Transport Proteins

Source

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Identifiers

PMID: 23383022
DOI: 10.1371/journal.pone.0054994
PMCID: PMC3559790

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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