Article
Transcriptome profiling of granulosa cells from bovine ovarian follicles during atresia.
BMC genomics - 18 Jan 2014
Hatzirodos Nicholas, Hummitzsch Katja, Irving-Rodgers Helen F, Harland Margaret L, Morris Stephanie E, Rodgers Raymond J
Abstract excerpt
BACKGROUND: The major function of the ovary is to produce oocytes for fertilisation. Oocytes mature in follicles surrounded by nurturing granulosa cells and all are enclosed by a basal lamina. During growth, granulosa cells replicate and a large fluid-filled cavity (the antrum) develops in the centre. Only follicles that have enlarged to over 10 mm can ovulate in cows. In mammals, the number of primordial...
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