Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity.

Science (New York, N.Y.) - 7 Feb 2014

Sayou Camille, Monniaux Marie, Nanao Max H, Moyroud Edwige, Brockington Samuel F, Thévenon Emmanuel, Chahtane Hicham, Warthmann Norman, Melkonian Michael, Zhang Yong, Wong Gane Ka-Shu, Weigel Detlef, Parcy François, Dumas Renaud

Abstract excerpt

Transcription factors (TFs) are key players in evolution. Changes affecting their function can yield novel life forms but may also have deleterious effects. Consequently, gene duplication events that release one gene copy from selective pressure are thought to be the common mechanism by which TFs...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arabidopsis Proteins
Share to DNA, Plant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Electrophoretic Mobility Shift Assay

Share to Evolution, Molecular

Share to Gene Dosage

Share to Plant Proteins

Share to Protein Structure, Tertiary

Share to Species Specificity

Source

Identifiers

PMID: 24436181
DOI: 10.1126/science.1248229

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24436181-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A promiscuous intermediate underlies the evolution of LEAFY DNA binding specificity.PMID 24436181Read ↗

Insights into the evolution and diversification of the AT-hook Motif Nuclear Localized gene family in land plants.Semantic proximity Read ↗

Arabidopsis thaliana leaf form evolved via loss of KNOX expression in leaves in association with a selective sweep.Semantic proximity Read ↗

Functional divergence and intron variability during evolution of angiosperm TERMINAL FLOWER1 (TFL1) genes.Semantic proximity Read ↗

A variant of LEAFY reveals its capacity to stimulate meristem development by inducing RAX1.Semantic proximity Read ↗

Gene co-option across scales shapes plant diversity.Semantic proximity Read ↗

Conservation vs divergence in LEAFY and APETALA1 functions between Arabidopsis thaliana and Cardamine hirsuta.Semantic proximity Read ↗

LEC1-LIKE paralog transcription factor: how to survive extinction and fit in NF-Y protein complex.Semantic proximity Read ↗

Antagonistic roles for KNOX1 and KNOX2 genes in patterning the land plant body plan following an ancient gene duplication.Semantic proximity Read ↗

Evolutionary divergence of LFY function in the mustards Arabidopsis thaliana and Leavenworthia crassa.Semantic proximity Read ↗

Relaxed selection among duplicate floral regulatory genes in Lamiales.Semantic proximity Read ↗

Molecular Evidence for Functional Divergence and Decay of a Transcription Factor Derived from Whole-Genome Duplication in Arabidopsis thaliana.Semantic proximity Read ↗

Protein interaction evolution from promiscuity to specificity with reduced flexibility in an increasingly complex network.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.