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Article

<scp>MicroRNA</scp>‐542‐3p inhibits tumour angiogenesis by targeting Angiopoietin‐2

9 Jan 2014

Abstract excerpt

Angiopoietin-2 (Angpt2) plays a critical role in angiogenesis and tumour progression. Therapeutic targeting of Angpt2 has been implicated as a promising strategy for cancer treatment. Whereas miRNAs are emerging as important modulators of angiogenesis, regulation of Angpt2 by miRNAs has not been established. Here we firstly report that Ang2 is targeted by a microRNA, miRNA-542-3p, which inhibits tumour...

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PMID: 24403060
DOI: 10.1002/path.4324

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