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Long Noncoding RNA Profiles Reveal Three Molecular Subtypes in Glioma

7 Jan 2014

Abstract excerpt

BACKGROUND: Gliomas are the most lethal type of primary brain tumor in adult. Long noncoding RNAs (lncRNAs), which are involved in the progression of various cancers, may offer a potential gene therapy target in glioma. METHODS AND FINDINGS: We first classified gliomas into three molecular subtypes (namely LncR1, LncR2 and LncR3) in Rembrandt dataset using consensus clustering. Survival analysis indicated that...

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PMID: 24393335
DOI: 10.1111/cns.12220

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