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Article

Diosgenin Inhibits hTERT Gene Expression in the A549 Lung Cancer Cell Line

30 Nov 2013

Abstract excerpt

BACKGROUND: Diosgenin, a steroidal saponin from a therapeutic herb, fenugreek (Trigonellafoenum-graceum L.), has been recognized to have anticancer properties. Telomerase activity is not detected in typical healthy cells, while in cancer cell telomerase expression is reactivated, therefore providing a promising cancer therapeutic target. MATERIALS AND METHODS: We studied the inhibitory effect of diosgenin on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 24377630
DOI: 10.7314/apjcp.2013.14.11.6945

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