Article
HBV genotype B/C and response to lamivudine therapy: a systematic review.
BioMed research international - 1 Jan 2013
Chen Xiu-Li, Li Man, Zhang Xiao-Lan
Abstract excerpt
A number of nucleoside analogues such as lamivudine (LAM), actually used for the treatment of chronic hepatitis B, can suppress HBV DNA replication, improve transaminase level and liver histology, and enhance the rate of hepatitis B e antigen (HBeAg) clearance. The responses to LAM therapy involve HBeAg clearance and HBV DNA conversion of negative. However, the associations between HBV genotype B/C and response...
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