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Article

Recovery of current through mutated TASK3 potassium channels underlying Birk Barel syndrome.

Molecular pharmacology - 1 Mar 2014

Veale Emma L, Hassan Mustafa, Walsh Yvonne, Al-Moubarak Ehab, Mathie Alistair

Abstract excerpt

TASK3 (TWIK-related acid-sensitive K(+) channel 3) potassium channels are members of the two-pore-domain potassium channel family. They are responsible for background leak potassium currents found in many cell types. TASK3 channels are genetically imprinted, and a mutation in TASK3 (G236R) is responsible for Birk Barel mental retardation dysmorphism syndrome, a maternally transmitted developmental disorder. This...

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Identifiers

PMID: 24342771
DOI: 10.1124/mol.113.090530

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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