Article
De novo copy number variations in cloned dogs from the same nuclear donor.
BMC genomics - 9 Dec 2013
Jung Seung-Hyun, Yim Seon-Hee, Oh Hyun Ju, Park Jung Eun, Kim Min Jung, Kim Geon A, Kim Tae-Min, Kim Jin-Soo, Lee Byeong Chun, Chung Yeun-Jun
Abstract excerpt
BACKGROUND: Somatic mosaicism of copy number variants (CNVs) in human body organs and de novo CNV event in monozygotic twins suggest that de novo CNVs can occur during mitotic recombination. These de novo CNV events are important for understanding genetic background of evolution and diverse phenotypes. In this study, we explored de novo CNV event in cloned dogs with identical genetic background. RESULTS: We...
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