Article
Toward composite molecular signatures in the phenotyping of asthma.
Annals of the American Thoracic Society - 1 Dec 2013
Wagener Ariane H, Yick Ching Yong, Brinkman Paul, van der Schee Marc P, Fens Niki, Sterk Peter J
Abstract excerpt
The complex biology of respiratory diseases such as asthma is feeding the discovery of various disease phenotypes. Although the clinical management of asthma phenotypes by using a single biomarker (e.g., sputum eosinophils) is successful, emerging evidence shows the requirement of multiscale, high-dimensional biological and clinical measurements to capture the complexity of various asthma phenotypes....
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