Phenotypes and disease characterization in chronic obstructive pulmonary disease. Toward the extinction of phenotypes?

Abstract excerpt

Chronic obstructive pulmonary disease (COPD) is a complex, heterogeneous disease. The severity of airflow limitation, traditionally used to guide therapy in patients with COPD, does not describe this complexity properly. As a result, over the past few years there has been a great deal of interest in characterizing COPD more precisely and identifying homogeneous groups of patients who respond to specific...

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