Article
Chronic obstructive pulmonary disease phenotypes: the future of COPD.
American journal of respiratory and critical care medicine - 1 Sept 2010
Han MeiLan K, Agusti Alvar, Calverley Peter M, Celli Bartolome R, Criner Gerard, Curtis Jeffrey L, Fabbri Leonardo M, Goldin Jonathan G, Jones Paul W, Macnee William, Make Barry J, Rabe Klaus F, Rennard Stephen I, Sciurba Frank C, Silverman Edwin K, Vestbo Jørgen, Washko George R, Wouters Emiel F M, Martinez Fernando J
Abstract excerpt
Significant heterogeneity of clinical presentation and disease progression exists within chronic obstructive pulmonary disease (COPD). Although FEV(1) inadequately describes this heterogeneity, a clear alternative has not emerged. The goal of phenotyping is to identify patient groups with unique prognostic or therapeutic characteristics, but significant variation and confusion surrounds use of the term...
Topics
- Disease Progression
- Forced Expiratory Flow Rates
- Forced Expiratory Volume
- Genetic Predisposition to Disease
- Humans
- Phenotype
- Prognosis
- Pulmonary Disease, Chronic Obstructive