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Article

GM2 gangliosidosis in British Jacob sheep.

Journal of comparative pathology - 1 Jan 2000

Wessels M E, Holmes J P, Jeffrey M, Jackson M, Mackintosh A, Kolodny E H, Zeng B J, Wang C B, Scholes S F E

Abstract excerpt

GM2 gangliosidosis (Tay-Sachs disease) was diagnosed in 6- to 8-month-old pedigree Jacob lambs from two unrelated flocks presenting clinically with progressive neurological dysfunction of 10 day's to 8 week's duration. Clinical signs included hindlimb ataxia and weakness, recumbency and proprioceptive defects. Histopathological examination of the nervous system identified extensive neuronal cytoplasmic...

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Identifiers

PMID: 24309906
DOI: 10.1016/j.jcpa.2013.10.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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