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Induction of Female-to-Male Sex Change in Adult Zebrafish by Aromatase Inhibitor Treatment

2 Dec 2013

Abstract excerpt

This study investigated whether undifferentiated germ and/or somatic stem cells remain in the differentiated ovary of a species that does not undergo sex changes under natural conditions and retain their sexual plasticity. The effect of aromatase inhibitor (AI)-treatment on sexually mature female zebrafish was examined. A 5-month AI treatment caused retraction of the ovaries after which testes-like organs...

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PMID: 24292399
DOI: 10.1038/srep03400

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