Article
Catalase and NO CATALASE ACTIVITY1 promote autophagy-dependent cell death in Arabidopsis.
The Plant cell - 1 Nov 2013
Hackenberg Thomas, Juul Trine, Auzina Aija, Gwizdz Sonia, Malolepszy Anna, Van Der Kelen Katrien, Dam Svend, Bressendorff Simon, Lorentzen Andrea, Roepstorff Peter, Lehmann Nielsen Kåre, Jørgensen Jan-Elo, Hofius Daniel, Van Breusegem Frank, Petersen Morten, Andersen Stig Uggerhøj
Abstract excerpt
Programmed cell death often depends on generation of reactive oxygen species, which can be detoxified by antioxidative enzymes, including catalases. We previously isolated catalase-deficient mutants (cat2) in a screen for resistance to hydroxyurea-induced cell death. Here, we identify an Arabidopsis thaliana hydroxyurea-resistant autophagy mutant, atg2, which also shows reduced sensitivity to cell death triggered...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.