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Reduction and expansion in microsporidian genome evolution: new insights from comparative genomics.

Genome biology and evolution - 1 Jan 2013

Nakjang Sirintra, Williams Tom A, Heinz Eva, Watson Andrew K, Foster Peter G, Sendra Kacper M, Heaps Sarah E, Hirt Robert P, Martin Embley T

Abstract excerpt

Microsporidia are an abundant group of obligate intracellular parasites of other eukaryotes, including immunocompromised humans, but the molecular basis of their intracellular lifestyle and pathobiology are poorly understood. New genomes from a taxonomically broad range of microsporidians, complemented by published expression data, provide an opportunity for comparative analyses to identify conserved and...

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PMID: 24259309
DOI: 10.1093/gbe/evt184
PMCID: PMC3879972

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