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Article

Optimizing Escherichia coli as a protein expression platform to produce Mycobacterium tuberculosis immunogenic proteins

19 Nov 2013

Abstract excerpt

BACKGROUND: A number of valuable candidates as tuberculosis vaccine have been reported, some of which have already entered clinical trials. The new vaccines, especially subunit vaccines, need multiple administrations in order to maintain adequate life-long immune memory: this demands for high production levels and degree of purity. RESULTS: In this study, TB10.4, Ag85B and a TB10.4-Ag85B chimeric protein...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 24252280
DOI: 10.1186/1475-2859-12-115

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