Article
Quantitative computed tomography-derived clusters: redefining airway remodeling in asthmatic patients.
The Journal of allergy and clinical immunology - 1 Mar 2014
Gupta Sumit, Hartley Ruth, Khan Umair T, Singapuri Amisha, Hargadon Beverly, Monteiro William, Pavord Ian D, Sousa Ana R, Marshall Richard P, Subramanian Deepak, Parr David, Entwisle James J, Siddiqui Salman, Raj Vimal, Brightling Christopher E
Abstract excerpt
BACKGROUND: Asthma heterogeneity is multidimensional and requires additional tools to unravel its complexity. Computed tomography (CT)-assessed proximal airway remodeling and air trapping in asthmatic patients might provide new insights into underlying disease mechanisms. OBJECTIVES: The aim of this study was to explore novel, quantitative, CT-determined asthma phenotypes. METHODS: Sixty-five asthmatic patients...
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