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Telomere biology: Cancer firewall or aging clock?

1 Sept 2013

Abstract excerpt

It has been a decade since the first surprising discovery that longer telomeres in humans are statistically associated with longer life expectancies. Since then, it has been firmly established that telomere shortening imposes an individual fitness cost in a number of mammalian species, including humans. But telomere shortening is easily avoided by application of telomerase, an enzyme which is coded into nearly...

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PMID: 24228928
DOI: 10.1134/s0006297913090125

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