Article
SNP rs2073618 of the osteoprotegerin gene is associated with diabetic retinopathy in Slovenian patients with type 2 diabetes.
BioMed research international - 1 Jan 2013
Mankoč Ramuš Sara, Kumše Tina, Globočnik Petrovič Mojca, Petrovič Daniel, Cilenšek Ines
Abstract excerpt
Recent studies indicate that osteoprotegerin (OPG) acts as an important regulatory molecule in the vasculature. Also, a strong association was observed between circulation OPG and microvascular complication. By considering the possible role of OPG in diabetic retinopathy (DR) we examined two of the most studied polymorphisms of the OPG genes rs2073618 (located in exon I) and rs3134069 (located in the promoter...
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