Article
Depth-dependent differences in community structure of the human colonic microbiota in health.
PloS one - 1 Jan 2013
Lavelle Aonghus, Lennon Grainne, Docherty Neil, Balfe Aine, Mulcahy Hugh E, Doherty Glen, O Donoghue Diarmuid, Hyland John M, Shanahan Fergus, Sheahan Kieran, Coffey J Calvin, Winter Desmond C, O Connell P Ronan
Abstract excerpt
OBJECTIVE: The aims of this study were to develop techniques for spatial microbial assessment in humans and to establish colonic luminal and mucosal spatial ecology, encompassing longitudinal and cross-sectional axes. DESIGN: A microbiological protected specimen brush was used in conjunction with a biopsy forceps to sample the colon in nine healthy volunteers undergoing colonoscopy. Terminal Restriction Fragment...
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