Article
Hemoglobin analyses in the Netherlands reveal more than 80 different variants including six novel ones.
Hemoglobin - 1 Jan 2014
van Zwieten Rob, Veldthuis Martijn, Delzenne Barend, Berghuis Jeffrey, Groen Joke, Ait Ichou Fatima, Clifford Els, Harteveld Cornelis L, Stroobants An K
Abstract excerpt
More than 20,000 blood samples of individuals living in The Netherlands and suspected of hemolytic anemia or diabetes were analyzed by high resolution cation exchange high performance liquid chromatography (HPLC). Besides common disease-related hemoglobins (Hbs), rare variants were also detected. The variant Hbs were retrospectively analyzed by capillary zone electrophoresis (CZE) and by isoelectric focusing...
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