Article
Preventing ovarian cancer through genetic testing: a population-based study.
Clinical genetics - 1 Nov 2014
Finch A, Bacopulos S, Rosen B, Fan I, Bradley L, Risch H, McLaughlin J R, Lerner-Ellis J, Narod S A
Abstract excerpt
Genetic testing for BRCA1 and BRCA2 gene mutations, in conjunction with preventive salpingo-oophorectomy for mutation carriers, may be used to prevent a proportion of invasive ovarian cancers ('personalized medicine'). We evaluated the potential utility of this approach at a population level by reviewing the pedigree information and genetic test results from 1342 ovarian cancer patients in Ontario. Of the 1342...
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