Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Propylthiouracil Versus Methimazole During Pregnancy: An Evolving Tale of Difficult Choices

1 Nov 2013

Abstract excerpt

Antithyroid drugs (ATDs) were introduced for clinical care more than six decades ago and revolutionized the treatment of hyperthyroidism (1). These drugs, however, were introduced well before current rigorous preclinical and clinical testing standards that include assessment of teratogenic potential. Early case reports described aplasia cutis associated with the use of methimazole (MMI) during pregnancy (2),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone health and treatments
Share to Congenital Ear and Nasal Anomalies
Share to Thyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24194618
DOI: 10.1210/jc.2013-3549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Propylthiouracil Versus Methimazole During Pregnancy: An Evolving Tale of Difficult ChoicesPMID 24194618Read ↗

Adverse effects of prenatal methimazole exposure.Semantic proximity Read ↗

Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential usesSemantic proximity Read ↗

Adverse Events During Pregnancy Associated with Third Generation Antiseizure Medications: A Real-World AnalysisSemantic proximity Read ↗

Antithyroid Drug Use in Pregnancy and Birth Defects: Why Some Studies Find Clear Associations, and Some Studies Report NoneSemantic proximity Read ↗

Ethical issues in therapeutic use and research in pregnant and breastfeeding womenSemantic proximity Read ↗

Evidence-Based Selection of Antiepileptic Drugs During Pregnancy: A Narrative Review of Safety and EfficacySemantic proximity Read ↗

Methimazole embryopathy: a contribution to defining the phenotype.Semantic proximity Read ↗

Optimizing responses to drug safety signals in pregnancy: the example of dolutegravir and neural tube defectsSemantic proximity Read ↗

Choanal atresia and hypothelia following methimazole exposure in utero: A second reportSemantic proximity Read ↗

Medicines in pregnancySemantic proximity Read ↗

Association between zidovudine and adverse pregnancy outcomes/congenital malformations: A pharmacovigilance study using FAERS dataSemantic proximity Read ↗

Thyrotropin receptor antibodies and a genetic hint in antithyroid drug-induced adverse drug reactions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.