Article
Virological response in patients with hepatitis C virus genotype 1b and a high viral load: impact of peginterferon-alpha-2a plus ribavirin dose reductions and host-related factors.
Clinical drug investigation - 1 Jan 2008
Yamada Gotaro, Iino Shiro, Okuno Tadao, Omata Masao, Kiyosawa Kendo, Kumada Hiromitsu, Hayashi Norio, Sakai Takahiro
Abstract excerpt
BACKGROUND AND OBJECTIVE: In Japan the prevalence of the hepatitis C virus (HCV) antibody is highest in the elderly population. Therefore, it is important for elderly patients to undergo interferon (IFN) therapy. In patients with HCV genotype 1b and a high viral load, the sustained virological response (SVR) rate is lower in older compared with younger patients receiving combination antiviral therapy. In...
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